Investors & Media

Investor FAQ

Investor FAQ

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Where are you located?
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010
(Carlsbad is approximately 35 miles north of downtown San Diego.)
Can you provide a brief description of your Company?

For three decades, Ionis has invented medicines that bring better futures to people with serious diseases. Ionis currently has five marketed medicines and a leading pipeline in neurology, cardiology, and other areas of high patient need. As the pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies in addition to advancing new approaches in gene editing. A deep understanding of disease biology and industry-leading technology propels our work, coupled with a passion and urgency to deliver life-changing advances for patients. 


To learn more about Ionis, visit and follow us on X (Twitter) and LinkedIn.

When was the Company founded and when did it go public?
Ionis Pharmaceuticals, Inc. was founded in 1989. Ionis conducted its initial public offering two years later in 1991.
What is Ionis’ stock symbol and on what exchange is it traded?
Ionis is traded on the NASDAQ stock exchange under the symbol IONS. Please note that prior to December 22, 2015 our symbol was ISIS and prior to February 21, 2002 our symbol was ISIP.
How can I get a copy of your annual report?
To view a PDF file of the annual reports from 2019-2022 click here. If you would like to receive a hard copy of any of Ionis' annual reports, please click here. Please note that if you are requesting that we send the annual report to an address outside of the U.S. (including Canada and Mexico) you must include your telephone number. The US Postal Service requires a phone number for shipments out of the U.S.
I have lost my stock certificates. How can I replace them?
Contact our Transfer Agent, American Stock Transfer & Trust Company: American Stock Transfer & Trust Company (AST)
6201 15th Avenue
Brooklyn, NY 11219 ATTN:
Shareholder Services
Tel 1-800-937-5449
Tel 1-718-921-8124
To begin the process, click here: After going to the website, shareholders can click Contact Us at the top right of the screen.