Analyst Coverage

Bank of America Merrill Lynch
Jason Gerberry
Barclays Capital Inc.
Eliana Merle
Goldman, Sachs & Co.
Salveen Richter
Guggenheim Securities
Debjit Chattopadhyay
H.C. Wainwright & Co.
Mitchell Kapoor
Jefferies & Company
Akash Tewari
J.P. Morgan Securities Inc.
Jessica Fye
Laidlaw & Company
Yale Jen
Leerink Partners
Mani Foroohar
Morgan Stanley & Co. LLC
Michael Ulz
Morningstar Research Services LLC
Rachel Elfman
Needham & Company, LLC
Joseph Stringer
Openheimer & Co. Inc.
Jay Olson
Piper Sandler
Allison Bratzel
RBC Capital Markets, LLC
Luca Issi
Sandford C. Bernstein & Co., LLC
William Pickering
Stifel Nicolaus
Paul Matteis
TD Cowen
Yaron Werber
Wells Fargo Securities, LLC
Yanan Zhu
William Blair & Company, L.L.C.
Myles Minter
Wolfe Research
Andy Chen

Ionis Pharmaceuticals, Inc. is followed by the analysts listed. Please note that any opinions, estimates or forecasts regarding Ionis Pharmaceuticals, Inc.'s performance made by these analysts are theirs alone and do not represent opinions, forecasts or predictions of Ionis Pharmaceuticals, Inc. or its management. Ionis Pharmaceuticals, Inc. does not by its reference or distribution imply its endorsement of or concurrence with such information, conclusions or recommendations.